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Evaluation of
Sun Sensitivity of the French Population.
Césarini, Jean-Pierre1
INSERM, Fondation A. de Rothschild1
Abstract-
Hundred volunteers have been selected from internal files of a sunscreen-testing
laboratory. They have been tested to determine their individual minimal
erythemal dose (MEDi) in a standardized fashion, according to COLIPA,
FDA, CIE, recommendations. In parallel, their phototypes have been established
according to a standardized questionnaire exploring several parameters:
hair color, freckling degree, tanning ability, burning at first sun-exposure
and natural acquired protection after 3 weeks of mild sun exposures.
MEDi was performed on their back and buttocks (solar simulator) together
with skin color evaluation with Minolta CR200 chromameter operating
in the L* a* b* system (CIE). The ITA angle is calculated after these
data. For each phototype I, II, and III (we excluded type IV from the
analysis because of the high frequency of ethnical mixtures), the MEDi
on the back and buttocks were found not significantly different. However
the ITA angle was significantly darker on the back than on the buttocks.
No significant difference was found for sex. When classified by increasing
ITA quartiles of the back, the MEDi of back and buttocks were decreasing.
However, for the first 2 quartiles, the MEDi of back and buttock were
not significantly different and for the 4th quartile, the MEDi of the
back was significantly lower than the buttocks MEDi. When analyzed by
increasing ITA quartiles of the buttocks, three classes of MED can be
clearly separated: very sensitive, intermediate sensitive, and low sensitive
on the back as well as on the buttocks. The ITA angle of the buttocks
is representative of sun sensitivity of the individuals and is well
correlated with the melanins contents of the epidermis which, in turn,
is correlated with the risk of developing skin cancers. The data support
the concept of melano-compromised (skin cancer prone) and melano-competent
(skin cancer resistant) populations.
Keywords: sun
sensitivity, erythema, skin color, skin cancer
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