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Attenuation at
670 nm as a Predictor of UV Sensitivity
Matchette, L. Stephanie1,
Lenderink, Egbert2, Zmudzka, Barbara1,
Miller, Sharon1 and Beer, Janusz1
Food and Drug Administration, Center for Devices and Radiological Health1
Philips Research Laboratories, Eindhoven, The Netherlands2
Abstract-
We are investigating the use of non-invasive optical techniques for
predicting the UV sensitivity of human skin. Some of these techniques
are based upon the measurement of red light attenuation by the skin.
Initial observations have been obtained using a prototype Optical Coherence
Tomograph (Philips Corp., The Netherlands). at 670 nm. The results for
11 human subjects representing skin types 1 to 5.5 from different racial/ethnic
origins strongly suggest that a correlation exists between the optical
attenuation of red light and the experimentally determined minimal erythemal
dose (MED). Another non-invasive measurement of skin light attenuation,
spatially resolved diffuse reflectance, is also being employed. Early
results obtained with this technique indicate that UV-induced erythema
affects not only the absorbance but also the scattering properties of
the skin. This technique may be an enhanced optical method for predicting
human skin UV sensitivity.
Keywords: UV,
skin, reflectance
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