29th Annual Meeting of the American Society of Photobiology

Downtown Marriot

Chicago, Il.

July 7th-12th, 2001


The Scientific Basis for Indoor Tanning Exposure Schedules

Sayre, Robert 1,2 and Caswell, Michael1
Rapid Precision Testing Laboratories, Cordova TN 380181
Dept. of Medicine, Div. Dermatology, Univ. of Tennessee Center for the Health Sciences, Memphis, TN 381632

Abstract-
Erythema and tanning responses have generally been studied by examining the biological response to single exposures of UV radiation. Until recently there have been few studies examining the risks and benefits of multiple UV exposure in human subjects. The indoor tanning industry is based upon the ability to promote UV-induced tanning without sunburn or erythema(1). Two groups of investigators have recently examined multiple UVA suberythemic exposures from xenon-arc solar simulators to groups of volunteers(2-4). The results of these studies suggest that skin injury may occur independent of erythema. During the more than 15 years in which indoor tanning has been using FDA approved tanning units, there has been only one report in when an indoor tanning unit was used to induce tanning following the FDA recommended exposure schedule for tanning(5). While every volunteer in this study developed a tan, more importantly no significant erythemic response was reported. Further follow up indicate that once tanning had occurred, it persisted through the final observation period, three weeks after the final exposure. Additional tan maintenance studies are necessary to determine an appropriate tan maintenance exposure schedule and to evaluate tan maintenance schedules for different skin types and for different tanning beds. References: 1. Sunlamp products and ultraviolet lamps intended for use in sunlamp products. 21CFR1040.20. 2. Lavker RM, Gerberick GF, Veres D, Irwin CJ, Kaidbey KH. Cumulative effects from repeated exposure to suberythemal doses of UVB and UVA in human skin, J Amer Acad Dermatol 1995;32:53-62. 3. Lavker RM, Veres D, Irwin CJ, Kaidbey KH. Quantitative assessment of cumulative damage from repetitive exposures to suberythemogenic doses of UVA in human skin. Photochem Photobiol 1995; 62:348-52. 4. Lowe NJ, Meyers DP, Wideer JM, Luftman D, Borget T, Lehman MD, Johnson AW, Scott IR. Low doses of repetitive ultraviolet A induce morphologic changes in human skin. J Invest Dermatol 1995: 105:739-743. 5. Caswell M. The Development of a Tan from Exposures to a Tanning Bed. Photoderm Photoimmun Photomed 2000; 16:10-14.

Keywords: tanning, erythema, UVA, exposure