29th Annual Meeting of the American Society of Photobiology

Downtown Marriot

Chicago, Il.

July 7th-12th, 2001


Optical Bio-diagnostics

Murray, George1
Johns Hopkins University Applied Physics Lab1

Abstract-
This talk will attempt to introduce some of the key concepts to be explored by this symposium. "Optical Bio-diagnostics" encompasses a broad overview of the means by which optical methods can be used to obtain relevant information about biological systems through processes that selectively monitor relevant chemicals. One aspect of the symposium is concerned with the application of optical sensing strategies to measure molecules of biological significance. Of particular interest are approaches to molecular recognition through biological or biomimetic means. The use of selective chemical receptors equipped with chromophores for sensitive detection has become a means for achieving both high selectivity and high sensitivity, unattainable by other means. Another key component of bio-diagnostics is minimally-invasive imaging. The combination of selective chemical recognition and imaging will be explored.

Keywords: bio-diagnostic, biomemetic, molecular recognition